What do B vitamins help with? B Vitamins: Side Effects

10.04.2021 | Documentation

Group B includes eight vitamins:

Vitamin B1 (thiamine);
Vitamin B2 (riboflavin);
Vitamin B3 (niacin, vitamin PP, nicotinic acid);
Vitamin B5 (pantothenic acid);
Vitamin B6 (pyridoxine, pyridoxal, or pyridoxamine);
Vitamin B7 (biotin, vitamin H);
Vitamin B9 (folic acid, folates, vitamin M, vitamin Bc);
Vitamin B12 (cobalamin, cyanocobalamin).

Vitamin-like substances

These substances are not included in the list of the main ones, since they are either produced by our body or are not vital. Their list:

(choline, adenine);
(inositol);
B10 (para-aminobenzoic acid, H1);
B11 (carnitine);
B13 (orotic acid);
B15 (pangamic acid);
B17 (laetral).

Interaction of vitamin B1 with other substances

When interacting with sulfites or nicotinic acid (for example, when connecting several medicines), thiamine is completely destroyed.
Thiamine destroys the antibiotics benzylpenicillin and streptomycin, so their simultaneous administration is unacceptable.
Despite the great popularity of complex preparations (such as Milgamma or Kombilipen), it is not recommended to administer vitamins B1 and B12 in one injection. The fact is that pyridoxine slows down the conversion of thiamine into its biologically active form, and cyanocobalamin increases the risk of developing allergic reactions to thiamine.
Thiamine weakens the effect of the muscle relaxant suxamethonium iodide and Ditilin.
Ethanol slows down the absorption of vitamin B1.
It is not recommended to mix thiamine with alkaline and neutral solutions, carbonates, citrates and barbiturates, with sodium hydrosulfite. In such combinations, the chemical structure of vitamin B1 becomes unstable.

Now you know everything about vitamin B1 (thiamine) - an extremely important chemical compound, without which life is impossible. Eat a varied diet, eat nuts and legumes, then you will never be affected by vitamin B1 deficiency, and the nervous and cardiovascular systems will remain highly efficient!

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daily requirement

The daily requirement of a person for vitamins varies depending on many factors: age, gender, health status, physical activity. It is important to satisfy the need for vitamins, since vitamin deficiency can cause great harm, undermining the proper functioning of organs and systems. Hypervitaminosis is no less dangerous - an excess of vitamins can cause many problems.

Table. The average daily human need for B vitamins

The need for vitamins of the group under consideration is increasing(but not higher than the upper allowable rate indicated in the table) with factors:

increased physical activity;
pregnancy, breastfeeding;
elderly age;
diets limited to foods containing B vitamins;
drinking alcohol, smoking;
stress, depression;
drinking a lot of coffee and tea;
chronic diarrhea;
the use of a considerable amount of sugar, sweets.

Why do women need vitamin B12?

Vitamin B12 is involved in many internal processes. Cyanocobalamin prevents fat cells from accumulating in the liver, protects against obesity, stimulates the active activity of leukocytes.

The daily dosage for women is 3 mcg, and nursing mothers should take no more than 4 mcg.

Vitamin-mineral complexes will help to fill the body's daily need for microelements. Vitamin B12 regulates the emotional state and brain activity.

The following advantages can be distinguished:

Help in the treatment of depression.
Improvement and normalization of sleep.
Increased blood circulation, quick adaptation to a sharp change in the regime of the day.
Vitamin contributes to the protection of nerve fibers from severe stress and excessive overexertion.
Aid in the normal absorption of amino acids.
Stimulation of bone formation, therefore, B12 vitamins are recommended to be taken in adolescence.

Note! Each person who takes vitamin-mineral complexes must comply with the established dosage.

An excessive amount of vitamin B12 in the body leads to urticaria, thrombosis, heart failure, and pulmonary edema.

It dissolves well in liquid, so negative symptoms are easily removed.

Food Sources of B Vitamins

Proper, varied nutrition- the guarantee of sufficient supply of the body useful vitamins group B.

Do not forget that many "B" components lose their properties or disappear during technical, thermal and other food processing. And also if they are stored incorrectly. Hence, an adjustment is required to draw up the need for products in order to obtain the daily requirement of vitamins.

Table. Sources of B group vitamins. Most Common Products

Vitamin name	Products	Quantity in 100 g	% of the average daily norm
Vitamin B1 (thiamine)	sunflower seeds	1.8 mg	120
	Flax seeds	1.6 mg	106
	Pork, tenderloin	1.4 mg	93
	Soy, peas, pistachios	0.9 mg	60
	Wheat bran, peanuts, hazelnuts	0.7 mg	46
	Liver: duck, goose, chicken. Rye bran, pink salmon caviar, lentils, beans, oatmeal, buckwheat	0.5 mg	33
	Beef and lamb kidneys, beef and pork heart, beef and pork liver, trout, chum salmon, kelp	0.3 mg	20
	Green peas, almonds, catfish, navaga, salmon, pink salmon	0.2 mg	13
Vitamin B2 (riboflavin)	Liver: pork, beef, lamb, chicken. Lamb and beef kidneys	2 mg	111
	Pork kidneys	1.5 mg	83
	Chicken heart, goose and duck liver, wheat germ flour	0.9 mg	50
	Quail egg, chicken egg white, almonds	0.7 mg	38
	Laminaria, champignons, chicken egg	0.5 mg	27
	White mushroom, oyster mushroom, turkey meat, trout, herring, cheese and homemade cottage cheese	0.3 mg	16
	Spinach, cottage cheese, yogurt, Brussels sprouts, sunflower seeds	0.2 mg	11
	Kefir, milk, fermented baked milk, oysters, walnuts, whole grain flour	0.15 mg	8
Vitamin B3 (niacin)	Pork liver, peanuts	17 mg	85
	Tuna, broiler chicken liver, sunflower seeds	15 mg	75
	Turkey, wheat bran, chicken liver, chicken, turkey	13 mg	65
	Rabbit meat, mackerel, pork kidneys, horse mackerel	11 mg	55
	Salmon, chum salmon	9 mg	45
	Pink salmon, lamb, goose and duck liver, sunflower seeds	8 mg	40
	Champignons, blue whiting, oyster mushroom, trout, carp, dried apricots, almonds	5 mg	25
	Brussels sprouts, spinach, asparagus, dill, green pea, avocado, celery, bell pepper, green peas	1.5 mg	8
Vitamin B5 (pantothenic acid)	Liver: pork, beef, duck, goose, lamb. Laminaria (dried)	6 mg	120
	beef kidneys, egg yolk, pork kidneys, porcini mushroom	3.5 mg	70
	Heart: beef, pork, lamb. Peas, wheat bran, champignons, trout	2.6 mg	52
	Quail egg, chicken, trout, salmon	1.65 mg	33
	Turkey, chicken egg, oyster mushroom	1.3 mg	26
	Tuna, veal, chum salmon, sunflower and flax seeds	1 mg	20
	Cauliflower, broccoli, green peas, yogurt, bran bread	0.8 mg	16
Vitamin B6 (pyridoxine)	pistachios	1.7 mg	85
	Garlic greens, wheat bran, chicken, sunflower seeds	1.3 mg	65
	Lamb and chicken liver, beans, soy	0.9 mg	45
	Salmon, mackerel, tuna, broiler chicken liver, goose and duck liver	0.8 mg	40
	Beef liver, sardine	0.7 mg	35
	Tomato paste, pink salmon, chicken	0.6 mg	30
	Pork kidneys and liver, beef kidneys, chum salmon, pork, sprat, turkey, pomegranate, rabbit meat, chickpeas, herring, flax seeds	0.5 mg	25
	Veal, beef, bananas, bell peppers, trout, catfish	0.35 mg	17
	Potato, Brussels sprouts, avocado	0.3 mg	15
Vitamin B7 (biotin)	sunflower seeds	670 mcg	1300
	Pork kidneys	140 mcg	280
	Beef liver and kidneys	90 mcg	180
	Pork liver, hazelnut	80 mcg	160
	soy, egg yolk	60 mcg	120
	Peanut	40 mcg	80
	Laminaria, corn, oatmeal, chicken egg, peas, walnut	20 mcg	40
	Almonds, mushrooms	16 mcg	32
	Cheese, cottage cheese, persimmon, millet	7 mcg	14
Vitamin B9 (folic acid)	Liver goose and duck,	730 mcg	182
	chickpeas	550 mcg	137
	Beans	450 mcg	112
	Beef and chicken liver, peanuts	240 mcg	60
	Lamb and pork liver, sunflower seeds	230 mcg	57
	Soya	200 mcg	50
	Hazelnut, parsley, cod liver	110 mcg	27
	Walnut, beans, lentils, flax seeds	90 mcg	22
	Avocado, spinach, beets, savoy and Chinese cabbage, wheat bran, walnut, broccoli	80 mcg	20
Vitamin B12 (cyanocobalamin)	Lamb liver	90 mcg	3000
	Liver: beef, goose, duck	55 mcg	1830
	Pork liver	30 mcg	1000
	Beef kidneys	25 mcg	830
	Chicken liver, oysters, pork kidneys	16 mcg	530
	Herring, mussels, mackerel, sardine, tuna	11 mcg	366
	Rabbit meat, chum salmon, pink salmon, trout	5 mcg	160

As you can see from the table, a lot of B vitamins are found in the same products. To get all the valuable B vitamins, you need to include in your diet ingredients such as:

Offal: liver, kidneys, heart;
Meat: pork, veal, beef, lamb, rabbit meat;
Fish: trout, salmon, pink salmon, tuna, herring, trout, carp;
Seeds: sunflower, flax, sesame;
Nuts: peanuts, almonds, walnuts;
Cereals: soybeans, peas, beans, millet, oatmeal, lentils;
Fruits and vegetables: persimmon, avocado, green garlic, parsley, spinach;
And also: kelp, eggs, cheese, cottage cheese, yogurt, fermented baked milk.

Recipes for foods fortified with thiamine

Taking into account the constant need of the body for the B1 compound, hypovitaminosis can be avoided by including foods containing a large amount of a water-soluble substance in the daily diet.

Consider recipes for dishes that can be easily prepared "on hastily» at home. At the same time, they will not only be tasty and nutritious, but will also help fill the lack of thiamine in the body.

Smoothie "Firstborn"

Ingredients:

cream with a fat content of 10% - 100 ml;
honeysuckle - 200g;
honey - 15 ml;
ice (snow) - 50 g;
mint (melissa, pepper).

Preparation description:

Rinse honeysuckle berries, grind in a blender.
Add honey, mint, cream, ice to the resulting mixture. Whisk all ingredients.
Pour a fortified drink into a glass.
When serving, garnish the smoothie with mint and a slice of lemon.

Warm salad with pine nuts

Ingredients:

olive oil - 60 ml;
lemon peel - 5 g;
lemon juice - 15 ml;
cherry tomatoes - 250 g;
zucchini - 1 pc;
sunflower seeds - 100 g;
pine nuts - 100 g;
soft feta cheese - 200 g;
parsley - a bunch;
mint;
salt;
pepper;
lettuce leaves.

Cooking technology:

Line a baking sheet with paper, which, in turn, needs to be greased with oil.
Cut the zucchini into circles, salt, pepper, put in a baking dish. The thickness of the vegetable should not exceed 5 mm.
Place a baking sheet with zucchini in a preheated oven for 15 minutes, maintaining the temperature in the oven at 180 degrees.
Cut mint, parsley, cheese, tomatoes.
Prepare the dressing. To do this, combine and beat the following products: salt, pepper, olive oil, zest, lemon juice.
Remove the toasted zucchini from the oven. Put them in a salad bowl, add chopped cherry tomatoes, herbs, cheese, sunflower seeds, pour dressing, mix.
Serve the dish in portions. To do this, put lettuce leaves on a plate, pour warm salad on them, sprinkle with pine nuts on top.

Vegetarian mediterranean salad

Ingredients:

cauliflower - 500 g;
bell pepper - 1 pc;
brown rice - 200 g;
pine nuts - 50 g;
almonds - 50 g;
onion - 1 pc;
dried cranberries - 100 g;
sesame seeds - 30 g;
lemon juice - 40 ml;
olive oil - 50 ml;
salt;
pepper.

Cooking sequence:

Rinse rice, boil (do not cool).
Onion, sweet pepper cut into strips.
Divide the cabbage into inflorescences, boil, discard in another shlag.
Rinse the cranberries, pour boiling water for 2 minutes, dry on a paper towel.
Combine all salad ingredients, salt, pepper, season with olive oil and lemon juice.
Serve the dish so that the rice in the salad is warm.

Useful properties and signs of shortage

B vitamins are responsible for the proper functioning nervous system, they reduce the negative impact of stressful situations. In addition, the compounds regulate metabolism, normalize blood sugar levels. Maintain muscle and skin tone. The immune system also needs to be supported by vitamins of this group. The components of the group improve the functioning of the cardiovascular and digestive systems.

The key role of B vitamins is to maintain cell health. With a lack of nutrients, they are depleted and eventually die. A group of vitamins regulates the formation of new cells. They are not allowed to randomly divide, which can lead to serious consequences in the form of the formation of cancer cells.

Thiamine (B1)

Thiamine, a vitamin of good mood and optimism is necessary for:

nervous system,
energy and carbohydrate metabolism,
cell energy,
of cardio-vascular system,
digestive processes.

Signs of a vitamin deficiency:

Irritability, depression, poor sleep, fatigue,
Disorders of the cardiovascular system, shortness of breath,
Digestive problems: constipation, lack of appetite.

Riboflavin (B2)

Riboflavin, the life energy vitamin, is essential for:

skin,
mucous membranes,
hair and nails
carbohydrate and fat metabolism,
cellular respiration and energy,
good vision,
growth and muscle mass.

Riboflavin deficiency symptoms can include:

hair loss,
peeling of the skin on the face,
pain in the eyes, increased photosensitivity,
inflammation of the tongue
small cracks on the lips.

Niacin (B3)

Niacin, a nerve cell saver, is essential for:

nervous system,
gastrointestinal tract,
skin,
carbohydrate, protein, fat metabolism,
respiration and cell energy,
good mood and sleep,
of cardio-vascular system,
maintaining normal cholesterol levels
muscles and connective tissues.

Deficiency symptoms:

depression, fatigue, poor sleep, distraction,
skin diseases,
mouth ulcers, gum sensitivity,
poor appetite, nausea, diarrhea,
headache.

Pantothenic acid (B5)

Vitamin participant of metabolism is necessary for:

health of the skin, hair and mucous membranes,
prevention of inflammation processes,
normal blood circulation
attention concentration,
slenderness and vigor,
prevent early aging and wrinkles.

Deficiency signs:

joint pain,
blurred vision,
cracks in the corners of the mouth,
irritability, depression,
memory impairment,
convulsions,
hair loss,
dermatitis, eczema,
constipation, digestive problems,
headaches, weakness, fatigue.

Pyridoxine (B6)

Vitamin of health and immunity is necessary for:

strong immunity,
formation of gastric juice,
good vision,
cardiovascular system and blood circulation,
normal hair growth
muscle activity,
nervous system,
protein digestion,
carbohydrate and fat metabolism.

Deficiency symptoms:

decreased appetite,
violation of the condition of the skin,
fatigue, muscle weakness,
irritability, depression,
cracks in the corners of the mouth,
hair loss,
limb numbness,
arthritis, circulatory disorders.

Biotin (B7)

Skin and hair health vitamin is essential for:

synthesis of fats and glycogen,
carbohydrate metabolism,
skin, nails, hair,
muscle and nerve cells.

Deficiency signs:

violation of the normal condition of the skin,
irritability, depression, depression,
oily or dry skin
hair loss,
gray color of the mucous membranes of the larynx and mouth,
muscle pain.

Folic acid (B9)

The Good Mood Vitamin is essential for:

normal growth and division of cells,
pregnant women for: proper development and bearing of the fetus,
cardiovascular health,
nervous system,
production of hydrochloric acid and good appetite,
proper functioning of the liver and gastrointestinal tract,
hair health,
brain work.

Signs of a folate deficiency:

in pregnant women: prematurity of the fetus and developmental disorders of the child,
anxiety, distraction, insomnia, forgetfulness, fear, fatigue,
inflammation of the tongue, mucous membrane of the lips,
anemia,
digestive disorders,
growth and development disorders.

Cobalamin (B12)

The most amazing and important vitamin is needed for:

proper functioning of the nervous system, as well as the brain,
good mood and optimism,
muscle activity,
energy metabolism, fat digestion,
normal growth and development,
metabolism, conversion of amino acids.

B12 and B9 are interconnected vitamins, they together participate in hematopoiesis.

Cobalamin deficiency symptoms:

nervousness, irritability, depression,
fatigue, difficulty moving,
limb numbness,
inflammatory processes in the oral cavity,
painful menstruation,
anemia, leukopenia.

Application

Many argue that, due to the fact that this vitamin complex plays a key role in converting food into energy and its impact on the body is great, it will be useful in a variety of situations, including anxiety, depression, heart disease and premenstrual syndrome (PMS).

In addition, some people take it to improve tone, improve mood and memory, improve skin and hair health, and to stimulate the immune system - these are the reasons why such vitamins are prescribed.

Most people who make sure their diet is rich and varied get enough vitamin B from food, but there are those who may not get enough, in particular those over 50 who take antacids, suffer from celiac disease, the disease Crohn's, gastritis or other digestive disorders - they drink vitamins separately.

If you've had fat removal or stomach surgery, drink alcohol regularly, or follow a vegetarian or vegan diet, you're at risk for a deficiency in this life-sustaining vitamin.

Pregnant and breastfeeding women may need more vitamins B6, B12 and folic acid - what they are for is very important for the formation of the fetus and in the first years of life.

Vitamin B deficiency

The symptoms of vitamin deficiency were discussed above separately. The following symptoms may indicate a lack of all components of group B:

Problems with the nervous system, depression, Bad mood, irritability, insomnia.
Violation of the condition of the skin.
Inflammation of the mucous membranes of the mouth and lips.
Visual impairment.
Digestive problems.
Limb numbness, muscle atrophy.
Breathing becomes difficult and the heartbeat quickens, in some cases dizziness is noted.
In addition, a lack of vitamin B can cause thinning and hair loss.
Patients become more sensitive to light.
Cholesterol rises to dangerous levels.

Vitamin B1 deficiency

In developed countries, vitamin B1 deficiency is rare, since people have the opportunity to eat a varied diet and consume at least a large number of thiamine-rich foods. However, with prolonged adherence to strict diets, thiamine reserves run out, which leads to the appearance of hypovitaminosis B1 with characteristic symptoms.

Beriberi disease (described at the beginning of the article);
Korsakov-Wernicke syndrome (Gaye-Wernicke);
Weakness and muscle atrophy up to cuts and paralysis;
Inflammation of nerve fibers and a decrease in mental activity, memory loss, orientation disorders in space and time, visual disturbances;
Digestive disorders and the appearance of ulcerative-erosive lesions on the mucous membranes.
Violations of the heart and blood vessels up to the development of heart failure.
The appearance of neurodermatological diseases such as psoriasis or eczema.

Excess B vitamins in the body

Dangerous and excess substances. With abnormal ingestion of B vitamins, intoxication begins. Excess compounds can cause allergies. The most dangerous and harmful, with excessive use, are substances B3, B6 And B9(upper allowable rates are indicated in the table of average daily rates, above) as they can cause disorders in the functions of the liver and gallbladder.

Manifestations are similar in nature to the symptoms of hypovitaminosis. Headaches, disorders of the vestibular apparatus, intestinal disorders, convulsions, numbness and insomnia are possible.

Signs and causes of vitamin deficiency in the body

Daily rate thiamine for a child - 0.5 - 1.7 milligrams, for women - 1.3 - 2.2, for men - 1.6 - 2.5.

During pregnancy, for the full formation of the fetus, the need for vitamin B1 increases and reaches 2.5 milligrams per day. The lack of a useful compound in the body carries a potential threat of improper laying of organs and the appearance of deviations in the work of the central nervous system of the unborn baby. Especially painfully a woman feels a deficiency of thiamine in the third trimester, when there is severe pain in the hips, lower back, due to the pressure of the uterus on the nerve plexuses. Therefore, it is important to ensure that a pregnant woman systematically compensates for the lack of a vitamin, consumes foods rich in the “hormone of happiness” daily.

Definition of hypovitaminosis B1

Primary symptoms:

numbness of hands, feet;
dysfunction of the brain;
increased irritability, tearfulness, feeling of anxiety;
chilliness, even at 25 degrees Celsius;
Wernicke-Korsakov syndrome (observed in patients suffering from alcohol dependence);
memory loss;
increased fatigue;
hand trembling;
insomnia;
headache;
depression;
feeling of depression;
muscle weakness;
deterioration in coordination;
diarrhea;
an increase in the size of the liver;
loss of appetite;
weight loss;
nausea;
gastrointestinal disorders;
burning in the epigastric region;
constipation;
arterial hypotension;
cardiopalmus;
unstable, rapid pulse;
shortness of breath with little exertion;
acute heart failure;
tachycardia.

In the complete absence of thiamine, a serious disease “take-take” occurs: harmful acids (lactic, pyruvic) accumulate in the body, carbohydrate metabolism is disturbed, the heart muscle, nervous system, and digestive tract are affected. There comes a sharp exhaustion, anorexia.

In view of the fact that the nutrient is not able to accumulate in the body, it is important to constantly replenish its reserves, otherwise beriberi gradually sets in.

Causes of vitamin B1 deficiency

Regular coffee intake. Daily consumption of a caffeinated drink results in the release of large amounts of hydrochloric acid, which destroys 50% of thiamine in the body.
Removal of coarse fiber (bran) from vegetable raw materials. Products "poor" in thiamine - polished rice, white bread, "extra" oatmeal, bleached grains.
Consumption of refined carbohydrate foods (bakery and confectionery, rich pastries, pasta). Regular intake of such products increases thiamine deficiency by 3 times.
Prolonged heat treatment of food. If food is cooked at a temperature of 200 degrees for 45 minutes, the loss of active thiamine reaches 50%.
Preservation of vegetables and fruits. Sterilization of products, for 20 minutes, leads to the loss of 25% of the vitamin.
Profuse sweating.
The presence of chronic infectious diseases.
Pregnancy. In the last trimester, a woman's need for a nutrient increases by 2 times. Therefore, for expectant mothers, the daily dosage of thiamine should be 3 milligrams.
Excessive heating or hypothermia of the body.

Thiamine deficiency for a long time (more than a year) leads to disruption of BJU metabolism and a decrease in the rate of formation of a cellular energy source. This means that the glucose ingested with food is not able to transform into ATP molecule As a result, toxic products of incomplete processing of carbohydrates (pyruvate, lactic acid) accumulate in the blood. These metabolites, penetrating the tissues of the brain and spinal cord, disrupt their proper functioning and provoke the development of neurological diseases. Timely identification and elimination of factors contributing to the deficiency of water-soluble vitamin in the body will help prevent the risk of such disorders.

Harmful properties of group vitamins

The main problem that can be encountered when using B vitamins is the lack of complexity. It is important to maintain a vitamin balance without neglecting other substances: in this way, beriberi can be avoided.

Subject to the average daily dosages, B vitamins are not dangerous. Many of them, even when exceeding the norm, are easily excreted by the body. But still, there are a number of side effects that can be observed when using the vitamins of the group in question. These include:

inflammation of the liver
change in blood sugar levels,
indigestion,
change in blood pressure,
disorder of the nervous system.

Normal side effects include discoloration of the urine.

Vitamin B1 during pregnancy

Thiamine, along with other vitamin and mineral compounds, is necessary for the full growth of the fetus and its intrauterine development. It is used for the normal course of all metabolic processes. Vitamin B1 is responsible not only for the energy supply of the baby's body, but also takes an active part in the formation of its nervous tissue. In addition, thiamine ensures the formation of a healthy heart, blood vessels and muscle fibers.

It is no less important for the pregnant woman herself, since it is involved in the functioning of the nervous system, it is necessary to maintain the mental and physical activity of the expectant mother. It also promotes rapid wound healing. Some experts claim that thiamine is the "vitamin of optimism" and improves mood. This, of course, is also important for bearing a healthy child.

Table. What destroys B vitamins and important points

vitamins	Destructive factors	Important Points
Thiamine	Alcohol	Vitamin C protects thiamine from premature destruction
Riboflavin	Light	Riboflavin degradation products destroy vitamin C
Niacin	acids	The body synthesizes B3 from the amino acid tryptophan, which is found in protein-rich foods.
Pantothenic acid	heating, alcohol	Vitamin is poorly absorbed in case of problems with the intestinal microflora
Pyridoxine	Light, heating	Foods that have undergone heat treatment lose up to forty percent of this vitamin.
Biotin	Preservation, frying	To preserve this vitamin, do not soak foods for long time or fry them
Folic acid	Light, heating	Vitamin C and iron promote better folate absorption
cobalamin	-	With low acidity of the stomach, the vitamin is poorly absorbed.

Characterization of thiamine

Today, many B vitamins have been discovered (B1, B2, B3, B5, B6, B9, B12, para-aminobenzoic acid, biotin, choline, inositol), which are actively involved in the course of vital functions: in metabolism, hematopoiesis, protein synthesis, fats, antibodies, hemoglobin, red blood cell formation, homocysteine metabolism, fetal development, regulation of nervous system activity. Their regular use can slow down the aging process and even reverse it.

The list of B vitamins is headed by thiamine, which is not able to accumulate in the body (see p. Causes of an increased need for thiamine).

As a result, in order to replenish the daily norm and prevent diseases associated with a deficiency of a substance, it is important to ensure its daily intake with food, supplements or medications.

Connection properties, how it is useful

It is a colorless crystalline substance with a pronounced yeast odor, measured in milligrams.
Dissolves in water. In fats, alcohol - no.
Easily digestible. When ingested, more than 60% of thiamine is absorbed into the blood by diffusion in the small intestine. The rest is broken down by the enzyme thiaminase, which is found in raw fish meat, and is also produced by intestinal bacteria in the body. Up to 5 milligrams of vitamin B1 can be absorbed per day. In some cases, this figure reaches 15, but this is a rare exception to the rule and depends on the characteristics of the body. The state of the gastrointestinal tract has a direct effect on the degree of absorption of thiamine. The presence of diseases digestive system(ulcer, colitis, gastritis, pancreatitis) reduces the absorption of the vitamin by 3 or more times.
The human or animal body daily produces an insufficient amount of vitamin B1 to meet the daily requirement for the substance. As a result, it must be regularly supplemented by introducing thiamine-rich foods or dietary supplements into the diet.
Cocarboxylase (thiamine diphosphate) is a coenzyme of vitamin B1. The mechanism of its formation is as follows: initially, the thiamine molecule enters the bloodstream, then it goes to the largest digestive gland - the liver, where it combines with phosphoric acid residues and, with the assistance of magnesium, turns into thiamine diphosphate. As part of the coenzyme, the particle is transported to tissues, organs, where it participates in the course of biochemical processes.
Resistant to acidic environment (with heat treatment up to 140 degrees). In alkaline or neutral solutions, thiamine is destroyed at 120 degrees or more. As a result, the addition of soda, ammonium carbonate to baking contributes to the rapid release and loss of vitamin B1.
Muscles contain 60% of thiamine, 40% is found in the adrenal glands, brain, liver, heart, kidneys.
Freezing foods rich in B1 by 50%, and sometimes completely, deprives them of a useful compound.
When adding salt to peas, beans during cooking, the loss of thiamine is 75%. To maximize the preservation of the vitamin, the dish must be flavored after cooking.
Lack of thiamine leads to beriberi, the development of the disease "take-take".
Vitamin B1 becomes biologically inactive under the action of sunlight.
Excess thiamine is non-toxic. With the use of vitamin B1 in large quantities (over 10 milligrams / day), after performing useful functions, the coenzyme molecule breaks down in the liver cells and, like the excess substance, is excreted in the urine.

Indications for admission

diagnosed B-vitamin deficiency;
neurological diseases;
increased emotional stress;
chronic fatigue;
headache;
sleep disorders;
cardiovascular pathologies;
circulatory disorders;
diseases of the respiratory system;
diseases of the digestive organs;
violation of metabolic processes;
endocrine disorders;
eye diseases (decreased visual acuity, cataracts);
skin diseases (eczema, dermatitis, acne, seborrhea);
damage to the skin and mucous membranes (wounds, ulcers);
dryness and hair loss, brittle nails;
osteochondrosis;
radiation sickness;
infectious processes;
anemia;
decreased immunity;
recovery period after illness;
active motor mode;
intensive sports training;
hard physical labor;
harmful environmental conditions.

Effects on hair and skin

Thiamine has a direct effect on the condition of the hair, but the deficiency of the compound in the body does not immediately affect the structure of the curls. In 95% of cases, the first symptoms of nutrient deficiency are fatigue, irritability, nervousness, tachycardia, muscle weakness, and a decrease in blood pressure.

Then, due to a violation of metabolic processes, the hair loses its natural luster, elasticity and strength. A daily intake of 1.5 milligrams of thiamine will help fill the lack of a nutrient. If within six months the physiological need for the vitamin is fully met, the process of gradual fastening of the hair scales will “start”, and as a result, the problems that have arisen will be eliminated.

Appointment of thiamine for hair:

strengthening curls;
increased hair growth;
slowing down the early appearance of gray hair;
increase in color brightness;
prevention of hair loss from the bulb;
elimination of dry or oily seborrhea;
saturation of the hairline with nutrients.

For accelerated restoration of the hair structure, in addition to oral administration, the drug can be additionally used externally, in the form of masks.

Ways to use vitamin in ampoules

Rubbing undiluted product into the scalp. For this purpose, solution B1 of one ampoule is used, which is used to treat clean hair roots. After applying thiamine, you need to wait 30 minutes, then thoroughly rinse off the vitamin mask with warm water. This procedure is carried out once every 7 days for 2 months.
Masks based on thiamine. Add 5 drops of liquid vitamin B1 to a portion of a cosmetic product (shampoo, conditioner, balm) and apply to the hair roots, evenly distributing the composition along the length. Wash off the mixture after 20 minutes.

Oral intake of the vitamin in combination with external hair treatment helps to eliminate the nutrient deficiency as soon as possible (in 3 months) and improve the functional state of the skin and curls.

Before using thiamine, it is important to adhere to the following rules:

Open the ampoule with a special file included in the package.
When breaking off the tip of the ampoule, use a cotton pad.
Do not use a solution opened a few hours ago. For the effectiveness of the procedures, the vitamin must be applied immediately after opening the vial, otherwise its effect is reduced by 50%.
Detangle and carefully comb the hair before the mask.
Apply thiamine with smooth movements to the hair roots. At the same time, it is important to avoid sudden intense actions that can damage weakened curls and lead to the bulb falling out.
Before using the substance, make sure that its expiration date has not expired.

When pain the mask should be washed off immediately.

Given the fact that vitamin B1 maintains the elasticity of the skin, it is advisable to use applications based on it for facial skin.

Problems that thiamine effectively fights:

wrinkles and sagging;
peeling;
excessive dryness of the skin;
inflammatory processes, acne;
vitamin deficiency of the skin;
profuse pigmentation.

If the smell of a vitamin causes vomiting, it is likely that the person is allergic to that substance. To detect a negative reaction of the body, a drop of pure B1 should be applied to the elbow bend and kept for 15 minutes. In the absence of redness or burning in the “checked” place, the nutrient can be applied to the face. Applications based on thiamine help to normalize metabolic processes in the skin and regulate the functioning of the sebaceous glands.

How to use B1 for face

Liquid vitamin is used in its pure form or in combination with other ingredients.
It is important to use the nutrient within 10 minutes after opening the ampoule.
The intensity of the use of undiluted "thiamine" applications - 2 times a week. The course of cosmetic procedures - 15 sessions. Cream enriched with vitamin B1 can be used daily.
Before starting therapy, the skin of the face is thoroughly cleaned of cosmetics, then the composition is applied for 15 minutes, avoiding the area around the eyes and lips. After the specified time, the mask is washed off with warm water, the face is dried with a towel.

After the course procedures, in 90% of cases, the skin looks toned, fresh and elastic.

Recipe for anti-aging mask with thiamine:

mix in equal proportions (15 milliliters each) warm linden honey, sour cream and cottage cheese (10 grams);
add an ampoule of vitamin B1 to the prepared mixture;
apply the composition to cleansed skin of the face and neck;
remove the remnants of the mask after 20 minutes;
wash your face with warm water.

With regular use of this mask, wrinkles become less noticeable, the complexion evens out and acne decreases.

Contraindications

B vitamins should not be taken:

with a tendency to allergic reactions;
B1 - women before and during menopause, children under eight years of age;
B2 - if there is urolithiasis, simultaneously with the treatment of psychiatric disorders, while taking hormonal contraceptives;
B3 - with gastric and duodenal ulcers in the acute phase, liver damage, gout, women during pregnancy and lactation, children under two years of age;
B5 - with kidney disease in the acute stage, hemophilia, intestinal obstruction, children under 3 years old.
B6 - with severe renal failure, gastric and duodenal ulcers during an exacerbation, coronary disease heart, functional disorders of the liver, diseases thyroid gland, children under 6 years;
B12 - during pregnancy, lactation, if there are such diseases as: angina pectoris, erythremia, erythrocytosis and thromboembolism.

B vitamins should be taken with caution and under the supervision of a specialist if the following disorders are present:

malignant formations;
diseases of the gastrointestinal tract;
gout.

Pregnant and lactating women, the elderly, children should be prescribed vitamins by a doctor.

The historical aspect of the appearance

At the beginning of the 20th century, the biochemist Funk was able to obtain a nitrogen-containing compound from rice bran. The substance alleviated the symptoms of the beriberi disease, accompanied by damage to the emotional, mental and cardiac functions.

Only after a while, in the middle of the last century, the scientist Williams was able to describe the structure of the vitamin molecule (C12H17N4OS), which marked the beginning of the synthetic production of the substance. At the same time, the trivial name "thiamine" appeared, which replaced the obsolete at that time "aneurine". In addition, there are two more names for the substance - thiamine pyrophosphate and thio-vitamin.

Best B Vitamin Complexes

Many foods do not contain enough vitamins. All this is due to such factors as: poor soils, dyes, preservatives, new technologies for processing and processing products. Therefore, specialists have developed preparations containing vitamins of group B. Of the highly effective complexes sold in pharmacies, the following can be distinguished:

RATIOPHARM VITAMIN B COMPLEX

average price- 2707 rubles. Manufacturer - Germany. The most effective of the premium drugs. Ratiopharm is a company that has won the trust of those who are used to taking care of their health. The complex includes all active compounds of the B-group. Ratiopharm Vitamin B Complex:

supports the nervous system;
controls protein metabolism;
increases efficiency;
strengthens the immune system.

With regular use of the drug:

mood improves;
increased concentration of attention;
the level of hemoglobin increases;
cells of the skin and mucous membranes are restored.

The disadvantages of this tool are the high cost and the possibility of side effects.

The complex can cause:

heartburn;
backlash (decrease in efficiency).

In most cases, the drug has a positive effect on the body: it improves well-being and improves immunity. The action of the multivitamin is approved by numerous reviews.

Kombilipen

Price - 470 rubles. Manufacturer - Russia. The complex contains vitamins B1, B6, B12. It is an analogue of the drug "Milgamma", intended for the treatment of neurological diseases.

The drug "Combilipen":

has an analgesic effect;
promotes the restoration of nerve tissues and myelin fibers.

Vitamin B1, which is part of the composition, has a fat-soluble form - benfotiamine, due to which its bioavailability increases several times. The complex contains high dosages of B1 and B6 (100 mg each) and a small dose of B12 (2 mg).

Contraindications to taking the drug:

cardiovascular insufficiency (acute and severe forms);
childhood.

Blagomax

The average price is 190 rubles. Manufacturer - Russia. The product is available in capsules. The package contains 90 pcs. The number of capsules is calculated for 3 months of admission (according to the instructions, the daily dose corresponds to 1 capsule). Blagomax is one of the best B-group complexes at an affordable price. Ingredients: vitamins B2, B3, B5, B6, B8, B9, B12.

Main functions:

stabilization of the nervous system;
acceleration of metabolism;
vasodilating action;
improvement of blood circulation;
normalization of hematopoietic processes;
lowering cholesterol levels;
improving the functioning of the digestive organs;
maintenance of visual processes.

Indications for admission:

increased physical and mental stress;
stressful conditions.

The effectiveness of the drug is confirmed by many positive reviews. The authors note that as a result of taking vitamins:

improves well-being;
irritability decreases;
the quality of sleep improves;
metabolism is normalized;
improves the condition of the skin, hair, nails.

The use of the drug is contraindicated in women during pregnancy and lactation.

Pentovit

Price - 112 rubles. Manufacturer - Russia.

The composition of the drug includes vitamins: B1, B3, B6, B9, B12.

Indications for use:

asthenic conditions;
neuralgia;
recovery period after illness.

The lack of a vitamin complex is a relatively large number of contraindications.

The drug should not be taken:

with chronic form of pancreatitis;
people suffering from gallstone disease;
women during pregnancy and lactation (nicotinamide, which is part of the composition, is toxic to the embryo and baby);
children under 18 years of age.

"Mega B Complex"

The complex contains all B group vitamins. "Mega-B Complex" supports the functioning of the nervous system, so it is especially needed for those who are constantly nervous or engaged in heavy physical labor. Due to the presence of calcium in the composition, the exchange of vitamins between the cell walls improves. This improves the overall positive influence on the body.

Vitamins protect cells and mucous membranes from aging, restore the integrity of the skin.

The entire daily norm of vitamins is contained in one tablet. Adults should take one tablet daily for 1-2 months.

The preparation contains the whole complex of vitamins of group B, is prescribed for severe hyperavitaminosis of vitamins B1 and B6 (neuralgic diseases of the musculoskeletal system). Increases blood flow, activates the nervous system.

The composition includes additional components:

Pyridoxine hydrochloride, which affects the process of protein metabolism;
Benfotiamine, a derivative of vitamin B1 involved in the oxidation of glucose;
carmellose sodium;
Incomplete glycerides of higher fatty acids;
Talc.

Pyridoxine is involved in the production of serotonin, the hormone of pleasure, which alleviates unpleasant symptoms in diseases.

Indications for use:

neuritis (paralysis or paresis);
retrobulbar neuritis (loss of vision);
neuralgia (peripheral nerve damage);
ganglionitis (inflammation of the ganglion - nerve node);
paresis of the facial nerve (impaired functioning of facial muscles);
lumbar ischialgia (back pain);
polyneuropathy, neuropathy;
plexopathy (damage to the nerve plexuses);
radiculopathy (sciatica).

The drug is taken 1-3 times a day for one month. One package containing 60 tablets (enough for a month or two) costs 1000 rubles.

"Angiovit"

Vitamin complex contains:

vitamin B12 (cyanocobalamin) - 0.006 milligrams;
vitamin B6 (pyridoxine hydrochloride) - 4 milligrams;
folic acid - 5 milligrams.

A specially designed complex is taken for: insufficient blood circulation of the brain, angiopathy (damage to blood vessels), diabetes, atherosclerosis.

The drug improves the metabolism of proteins, in particular methionine (an essential amino acid), as well as its catalysts (process accelerators). Therefore, the complex prevents diseases such as:

vascular atherosclerosis;
arterial thrombosis;
ischemic cerebral stroke;
heart attack (myocardium);
diabetic vascular disease);
chronic miscarriage of the fetus;
congenital pathology in a child.

Angiovit is useful in the treatment of elderly dementia, depression, Alzheimer's disease.

Vitamins are rapidly absorbed in the intestine after ingestion. Contraindications are only individual intolerance to the components. Side effects rarely occur in the form of allergies: swelling, urticaria, skin itching. Tablets should not be chewed or crushed, they must be swallowed and washed down with water.

The duration of the treatment course is 20-30 days. You need to take one tablet per day better in the morning. So the body will be saturated with a complex of vitamins of group B for the whole day.

"Neuromultivit"

This complex includes:

vitamin B1 - 0.1 grams;
vitamin B6 - 0.2 grams;
vitamin B12 - 0.2 grams.
and other excipients: microcrystalline cellulose, magnesium stearate, povidone + components included in the tablet shell.

In addition to group "B", it also contains vitamins: A, D3, C, as well as minerals: calcium, phosphorus, which help their absorption.

You can not take the drug:

Pregnant, lactating mothers;
Children under 12;
Patients with diabetes;
Hypersensitive to the components of the complex;

The active components of the drug - B1, B6 and B12 - are used in the treatment of not only beriberi, but also diseases that do not depend on metabolism: pain syndrome, polyneuritis, psychosis.

Indications for the use of the drug are:

trigeminal neuralgia;
polyneuritis (diabetic and alcoholic polyneuropathy);
neuritis (inflammation of peripheral nerves);
damage to the sciatic nerve caused by its inflammation or compression (sharp back pain) and lumboischialgia;
radicular syndrome (sciatica);
neuropathy of the facial nerve.

Possible side effects: nausea, tachycardia and skin rash.

Neuromultivit should be taken "whole", without crushing the tablet, immediately after a meal. Number of doses per day: from one to three. You need to take the drug for no more than one month.

Gerimaks

Ingredients: all the necessary vitamins of group B, as well as vitamins of other groups, minerals, extracts: ginseng, green tea.

It is excellent for insomnia, heavy physical and mental stress. After a working day, energy remains, a person feels invigorated due to ginseng extract. The drug helps with beriberi, increases energy metabolism.

Who should not take:

Teenagers under 16;
Patients with excess calcium in the body;
With increased sensitivity and excitability;
Patients with hypertension.

Who needs to take:

People experiencing stress when playing sports or strenuous studies;
Patients during the rehabilitation period;
Insomniacs;
With a lack of vitamins and minerals.

In case of an overdose, skin itching, digestive and sleep disturbances are possible. It is best to take Gerimaks after breakfast.

Taking drugs with B vitamins will certainly help to establish metabolism and cure diseases. You just need to play it safe and consult with your doctor, because the complexes, as you have seen, are different and this moment there are many of them.

Afterword

To stay healthy, most people can get everything they need if they eat a varied, balanced diet with vitamin B rich foods such as leafy greens, nuts, legumes and grains, dietary protein, mushrooms, and eggs. If you are not deficient in vitamin B, there is no need to take extra, but sometimes there are indications for use.

If you are not getting enough synthesized vitamin B from food, then it may be helpful to turn to nutritional supplements, whose effect on the body is beneficial. Its deficiency can lead to a range of symptoms, including fatigue, anemia, loss of appetite, depression, abdominal pain, muscle cramps, hair loss and eczema.

Most importantly, do not forget to consult with your doctor and find out which vitamin complex is right for you (and if you still need it, how much of it you need, taking into account what you get from food and other sources).

Disclaimer: The information contained on this site is for educational purposes only and is not a substitute for advice, diagnosis, or treatment by a licensed physician. It is not intended to cover all possible precautions, drug interactions, circumstances or side effects. You should seek medical attention for any health issues and consult your doctor before using alternative medicine or making changes to your regimen.

Conclusion

Vitamins "B" are indispensable for the body. It is important to prevent the appearance of a deficiency of nutrients.

And also we must not forget about the overabundance of these vitamins, which can harm the body.

When choosing one or another vitamin complex of this group, consult your doctor.

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The history of the discovery of vitamin B1

The detection of vitamin B1 is associated with the pathology "beri-beri", which in fact is a pronounced deficiency of B1 and means "hurts - hurts." Now such diseases, fortunately, practically do not occur. It was common at the beginning of the 20th century among the inhabitants of Asian countries, who ate mainly white rice. Rice stripped of its shell did not provide the daily intake of vitamin B1, as a result of which people suffered from various disorders of the brain and peripheral nerves (the so-called "dry vitamin deficiency B1"), as well as the cardiovascular system (or "wet vitamin B1 deficiency", which accompanied by severe edema).

Typical appearance of a beriberi patient

Patients with "beri-beri" experienced poor appetite and nausea, frequent constipation, constant pain and tingling in the limbs, sleep disturbances up to insomnia, frequent mood swings, a significant decrease in mental and physical activity. Soreness in the calf muscles when walking did not allow even daily activities. In the extreme stage, paralysis of internal organs and muscles developed. Damage to the heart and blood vessels led to edema, lowering blood pressure and the development of heart failure.

A close study of this pathology by a Dutch doctor and Nobel laureate Christian Aikman(Christiaan Eijkman) led him to assume that the grains of rice contained some kind of paralytic substance. At the same time, rice bran contains beneficial substances that prevent the development of the disease.

As early as 1911, the Polish-American biochemist Kazimierz Funk received a bioactive substance from rice bran, later called simply “vitamin” (from the Latin vita + amin).

In 1926 the Dutch biochemist Barend Coenraad Petrus Jansen And William Frederick Donat isolated from rice bran pure vitamin B1 in crystalline form. Historically, it was the very first pure vitamin. Hence the name "B1", i.e. vitamin number 1.

It is noteworthy that one of the names of vitamin B1 is aneurin. It refers to a substance that prevents damage to the nervous tissue. Later, due to its chemical (amine) structure, vitamin B1 became known as thiamine(lat. Thiamine). This name stuck with him and is widely used to this day.

Benefits and Benefits for Human Health

#1 Treatment for Wernicke-Korsakoff Syndrome

Wernicke-Korsakoff syndrome is one of the most severe neuropsychiatric consequences of alcohol abuse. The authors of the 2013 Cochrane review of thiamine for the treatment or prevention of Wernicke-Korsakoff syndrome found only two studies that met their inclusion criteria, and one of these studies was not published.

These randomized, double-blind, placebo-controlled trials compared 5 mg/day orally for 2 weeks or daily intramuscular doses of thiamine from 5 to 200 mg/day for 2 consecutive days in 177 people with a history of chronic alcohol use. The authors of the Cochrane review concluded that there is insufficient evidence from randomized clinical trials to provide guidance to healthcare professionals on the appropriate dose, frequency, duration, or route of administration of thiamine for the treatment or prevention of Wernicke-Korsakoff syndrome in patients who abuse alcohol.

The authors of the European Federation of Neurological Societies guidelines for the diagnosis, prevention and treatment of Wernicke's encephalopathy note that even high doses of oral thiamine supplements may not be effective in increasing blood levels of thiamine or treating Wernicke's encephalopathy. They recommend 200mg of thiamine, preferably intravenously, three times a day (600mg/day total) until signs and symptoms subside, along with a balanced diet.

In their guidelines for the management of Wernicke's encephalopathy in emergency departments, the Royal College of Physicians London supports the administration of oral thiamine hydrochloride (100 mg three times daily) to patients with adequate dietary thiamine intake and no signs or symptoms of Wernicke's encephalopathy. However, the authors recommend parenteral thiamine supplementation for high-risk patients, such as those with ataxia, confusion, and chronic alcohol abuse, because oral supplementation is unlikely to provide adequate blood levels.

#2 Preventing Beri Beri Disease

The most common effect of thiamine deficiency is beriberi (Beriberi disease), which is characterized mainly by peripheral neuropathy and malnutrition. People with this disease have impaired sensory, motor, and reflex functions.

Beri-Beri is most commonly seen in people who abuse alcohol, but may also be associated with other etiologies leading to thiamine deficiency.

Initially, symptoms of beriberi are nonspecific and include constipation, appetite suppression, nausea, mental depression, fatigue, peripheral neuropathy, anorexia, and weight loss. With progression chronic symptoms may begin to manifest as wet beriberi or dry beriberi. Wet beriberi have edema, an enlarged heart, heart failure, warm extremities, pleural effusions, and pulmonary edema. Meanwhile, the complications of dry avitaminosis are predominantly neurological with damage to the peripheral nervous system. People with dry beriberi may have paresthesia, foot drop, muscle atrophy, numbness, and lack of ankle reflexes.

In rare cases, beriberi causes congestive heart failure, which leads to swelling in the lower limbs and, sometimes, to death. Although beriberi is rare in developed countries, people in these countries sometimes get sick [ , ]. The introduction of additional thiamine, often parenterally, quickly cures beriberi.

#3 Diabetes mellitus

Some small studies have shown that oral thiamine supplements 150–300 mg/day can lower glucose levels in patients with type 2 diabetes or impaired glucose tolerance [ , ]. However, the authors of these studies did not assess the potential clinical relevance of these findings.

Several small randomized trials have evaluated the effects of benfotiamine supplementation on diabetic neuropathy. Three studies found that, compared with placebo, benfotiamine 120–900 mg/day with or without other B vitamins reduced neuropathic symptoms and decreased urinary albumin excretion (a marker of early-stage diabetic nephropathy) [ , ]. However, another study found no effect of 900 mg/day benfotiamine on urinary excretion of albumin.

Well-designed studies with larger sample sizes and longer durations are needed to determine whether thiamine supplementation can lower glucose levels in patients with diabetes or reduce diabetic complications.

#4 Heart failure

Rates of poor thiamine status in heart failure patients ranged from 21% to 98% across studies. Explanations for this association include advanced age, comorbidities, insufficient food intake, diuretic treatment, and frequent hospitalizations.

The authors of one study reported that 33% of 100 patients with chronic heart failure were deficient in thiamine compared to 12% of 50 healthy volunteers. The deficiency rate was even higher when the researchers excluded those who took thiamine supplements. The varying incidence of thiamine deficiency in patients with heart failure in these and other studies is likely due to differences in nutritional status, comorbidities, medications and dietary supplements used, and methods of measuring thiamine status.

The authors of a systematic literature review and meta-analysis found two randomized, double-blind, placebo-controlled trials of thiamine supplementation in people with heart failure that met their eligibility criteria. In these studies, thiamine supplementation significantly improved the net change in left ventricular ejection fraction. However, the authors did not assess the clinical significance of this finding.

More research is needed to determine if thiamine supplements can help people with heart failure, even if they have a normal thiamine status.

#5 Alzheimer's disease

According to animal model studies, thiamine deficiency may play a role in the development of Alzheimer's disease. For example, thiamine deficiency causes oxidative stress in neurons, neuronal death, memory loss, plaque formation, and changes in glucose metabolism are all markers of Alzheimer's disease. Autopsy studies have shown that transketolase and other thiamine-dependent enzymes reduce brain activity in people with Alzheimer's disease [ , ].

Few studies have assessed the prevalence of thiamine deficiency in people with Alzheimer's disease. One of these studies found that 13% of 150 patients with cognitive impairment and acute behavioral disorders were considered thiamine deficient based on plasma levels.

The authors of a 2001 Cochrane review evaluated three double-blind, randomized trials (including two crossover trials) comparing the effects of oral thiamine 3 g/day with placebo on cognitive function in patients with Alzheimer's dementia. Three studies randomly assigned fewer than 20 patients. The review authors stated that it was not possible to draw any conclusions from these three studies because they were small and the publications that described them did not provide enough detail to combine these data in a meta-analysis.

Larger, well-designed studies are needed to determine whether thiamine supplements are beneficial for treating Alzheimer's disease.

#6 Cataract

Recent studies show that thiamine may reduce the risk of developing cataracts. These studies show that people who consume a lot of protein along with vitamins A, B1, B2 (riboflavin) and B3 (niacin) in their diet are less likely to develop cataracts. Getting enough vitamins C, E and B vitamins additionally protects the lens of the eye ().

#7 Benfotiamine, a Thiamine Analogue, Can Suppress Cancer Growth

Benfotiamine has been shown to inhibit the growth of leukemic tumors in cell studies by promoting cell death and enhancing the effects of chemotherapy.

Benefit for health

The above processes affect general state organism, the work of internal organs and systems. As a result, the properties of the outer covers are improved, since tissue nutrition is normalized.

Vitamins of group B promote hair growth, help to keep them in good condition: they affect the pigment, the work of the sebaceous glands.

This means that preparations based on these components provide a complex effect on the body. They not only improve the appearance of curls, but also eliminate the causes of the pathological condition.

Functions of thiamine in the body

Thiamine affects almost all body systems, providing a therapeutic and prophylactic effect. This is due to its functions in the body.

metabolic

ensuring the correct course of metabolic processes;
production of energy molecules ATP;
absorption of proteins and fats from food;
production of blood cells.

nervous

the formation of myelin sheaths around nerve endings;
mood enhancement;
memory improvement;
depression treatment;
reducing the impact of stress;
treatment of cerebellar syndrome.

Cardiovascular

ensuring the normal functioning of the ventricles of the heart;
treatment of arrhythmias;
prevention of heart failure.

digestive

maintaining the muscle tone of the digestive tract;
normalization of the secretion of hydrochloric acid.

visual

prevention of glaucoma and cataracts;
strengthening the eye muscles;
protection of the optic nerve.

Mistakes that lead to a decrease in vitamin B1 levels

You should not assume that by eating a handful of sunflower seeds or a couple of nucleoli pine nuts, you can not worry about the level of thiamine in the blood: the need for this substance, as well as its absorption, can vary significantly depending on the physiological characteristics of the body, addictions and lifestyle of the person himself. The most common mistakes are as follows:

Thiamine is rapidly destroyed by heat treatment. This once again proves that fresh products are much healthier and more nutritious than cooked ones.
In an acidic environment, vitamin B1 is more resistant to high temperatures than in an alkaline and neutral one. That is why baking soda contains a lower percentage of thiamine than a similar dessert without sodium bicarbonate.
Freeze useful products in the freezer leads to partial destruction of thiamine molecules. Depending on the specific type of food product, the damage caused can vary between 50-90% of the original level of the vitamin.
Canned foods are depleted in vitamin B1 even if critically high temperatures were not reached during their preparation. In just half an hour of sterilization, without which safe preservation is impossible, up to 40% of thiamine is destroyed.
Coffee drinkers should double or even triple their daily intake of vitamin B1, as the invigorating drink stimulates the production of hydrochloric acid, which in large doses inhibits the action of thiamine.

Eat healthy foods, rationally approach menu planning, follow the correct lifestyle without waiting for dangerous symptoms - this is the only way you can maintain your own health and good spirits. long years life!

Usage

The role of vitamin B1 in the body is great, so it is often prescribed. It is useful for:

B1 deficiency;
chronic diseases of the digestive organs, accompanied by low acidity and impaired absorption of food in the intestine;
cirrhosis of the liver;
polyneuritis;
exhaustion;
muscle weakness;
heart disease with heart failure;
angina pectoris, myocardial infarction;
myocardial dystrophy - the so-called metabolic diseases of the heart muscle;
skin diseases accompanied by itching (eczema, psoriasis, shingles, etc.);
chronic alcoholism;
lactation disorders - stimulates the production of women's milk;
poisoning;
as part of complex therapy to eliminate pain;
infants who eat only semolina.

Vitamin B 1 is produced in the form of drugs and biologically active food supplements (BAA). These funds are called differently. How to take drugs with vitamin B1, the doctor determines.

Benfogamma - 1 tablet contains 150 mg of a fat-soluble vitamin with high bioavailability; the tablet should be taken 1 time per day, after meals; the drug is especially useful in neurological diseases;
Thiamine chloride and thiamine bromide - the dosage of a water-soluble compound in tablets can range from 2 to 100 mg; take half an hour before meals; for prophylactic purposes, adults are prescribed 5 mg daily, children from 3 to 8 years old - 2 mg each, up to 3 years old - 1 mg each.
Phosphotiamine - the active substance is monofostiamine - phosphoric ester of thiamine; prescribe 10 mg after meals for a course of 3 to 4 weeks.

Solutions in ampoules with vitamin B1 (thiamine) are prescribed only by a doctor strictly according to indications. The most effective drug is cocarboxylase - active thiamine, necessary to increase the energy potential of cells, is produced in the form of a powder in ampoules for the preparation of an injection solution.

Recipe for tablets:
Rp.: Thiamin chloridi 0.002
D.t.d. No. 50 in tab.
S. Take 1 tablet 3 times daily

Scalp massage with vitamins

You can apply the above means in another way - by rubbing into the scalp. In this case, the active components fall directly to the lesion. You will need cyanocobalamin, thiamine or pyridoxine hydrochloride.

If the symptoms of the disease are mild or moderate, it is enough to choose one substance - 4 ampoules. It is permissible to combine them: take 2 types of vitamins (2 ampoules of each).

The solution must be prepared in a plastic or porcelain dish. If you do not follow this recommendation, useful substances will quickly collapse.

The head must first be washed. The composition is applied with a syringe, it is rubbed with fingertips. For convenience, it is recommended to separate the curls with partings. After processing, it is not necessary to wash off the product.

Useful substances that are used for massage do not stain the scalp. After the procedure, it is permissible to dry the hair with a hairdryer. The frequency of performing massage - 3 times a week. Course duration - 1 month.

Head massage with B vitamins.

Foods Rich in Vitamin B1

wholemeal wheat bread
cereals (coarse rice, oatmeal, buckwheat, millet)
legumes (soybeans, beans, green peas, lentils)
greens (spinach, parsley, onion)
vegetables (asparagus, broccoli, spinach, potatoes, carrots, white cabbage, Brussels sprouts, pumpkin, cauliflower, tomatoes, beets, eggplant)
offal (liver, kidneys, lungs, heart, stomach, brain)
meat (pork, beef)
egg yolk
yeast (beer)
algae (kelp, spirulina)
milk
nuts (pine nuts, pistachios, peanuts) and sunflower seeds
fruits and berries (oranges, rose hips, plums, strawberries, blueberries, black currants, sea buckthorn)
dried fruits (prunes, raisins)
herbs (alfalfa, peppermint, raspberry leaf, sage, clover, sorrel, burdock root, catnip, cayenne pepper, fennel seeds, chamomile, fenugreek, hops, nettle, oat straw).

Physico-chemical features

Vitamin B1 is a crystalline powder with high biological activity. It is soluble in water but insoluble in alcohol. There is also a fat-soluble synthetic derivative of thiamine - benfotiamine. When heated, vitamin B1 decomposes and loses its healing properties. There are four forms of this substance in the human body:

unphosphorylated thiamine,
thiamine monophosphate,
thiamine diphosphate (thiamine pyrophosphate - TPP, TDP, cocarboxylase) - the most common active form,
thiamine triphosphate (TTP) is an understudied form.

The chemical formula is C12H17N4OS.

The biological properties of vitamin B1 are due to the action of TPP (TDF), which is formed from thiamine and ATP in the presence of the enzyme thiamine kinase. This active form of vitamin B1 is a coenzyme (component) of enzymes that play an important role in metabolic processes. Enzymatic reactions involving TPP (cocarboxylase):

It is a transketolase coenzyme involved in the renewal of liver cells, erythrocytes, adrenal cortex, etc. These enzymatic reactions of glucose oxidation are not associated with the formation of energy, they provide protein synthesis processes.
As a coenzyme for the enzymes pyruvate dehydrogenase and α-ketoglutarate dehydrogenase, it is involved in energy metabolism. The received additional energy goes to the activation of all metabolic processes.
As a coenzyme dehydrogenase contributes to the breakdown of a number of amino acids.

It is believed that such a little-studied form as TTP is involved in the formation of the neurotransmitter acetylcholine and the transmission of impulses through the nervous system.

Composition and characteristics of B vitamins

This group includes:

Characteristics and properties of B vitamins.

Vitamin B1. It is a water-soluble substance, its other name is thiamine. Main characteristic is intolerance high temperature(the vitamin starts to break down). With its participation, metabolic processes develop: proteins, fats, carbohydrates are transformed in the body, thanks to which the substance contributes to the normalization of the nutrition of the scalp, hair follicles. It is contained in soft tissues, but does not accumulate, because it dissolves in water. Other functions: stimulation of cell growth, restoration of the nervous system, which also helps to improve the condition of the hair.
Riboflavin, or vitamin B2. It is a water-soluble substance, which means that it is quickly destroyed in the body. Participates in most metabolic processes, since it is a coenzyme. The main function is to maintain redox reactions. Thanks to them, harmful substances are destroyed, and useful compounds, on the contrary, are protected from the negative effects of free radicals. This improves the condition of soft tissues (scalp) and hair. Riboflavin affects the functioning of the sebaceous glands, activates regeneration.
Vitamin B3, also called niacin or nicotinic acid. This substance also affects metabolic processes, participates in the transformation of lipids, carbohydrates, proteins, restores tissue respiration, and lowers the concentration of low density lipoproteins. Vitamin improves blood circulation due to the ability to dilate blood vessels. These processes allow you to activate the nutrition of the scalp and hair. The substance affects pigmentation, and also gives shine and strength.
Vitamin B4. Another name is choline. It releases the neurotransmitter acetylcholine. With his participation, the process of transmission of nerve impulses is realized. Vitamin affects carbohydrate metabolism, performs the function of a hepatoprotector, is involved in the transport of fats. This means that it acts on the scalp and hair indirectly, normalizing internal processes in organism.
Pantothenic acid, or vitamin B5. The substance affects metabolic processes. Its main function is the transport of carboxylic acids. Thanks to this vitamin, hair loss stops, their condition normalizes, since it affects the production of hormones.
Vitamin B6 (adermine). Most often, one of the derivatives, pyridoxine hydrochloride, is used to restore body functions. In its pure form, the component is not used. The substance is involved in metabolism, affects the synthesis of neurotransmitters, histamine, hemoglobin. As a result, the condition of tissues and hair is normalized, since the work of the nervous system improves, tissue respiration is restored.
Biotin, or vitamin B7. The substance is involved in the metabolism of fatty acids, carbohydrates, proteins, the process of gluconeogenesis, promotes the synthesis of collagen, thereby improving the condition of tissues and hair.
Vitamin B8 (inositol). It is part of enzymes, affects lipid metabolism, normalizes cholesterol levels. This means that it is used to improve the condition of the hair as an indirect measure of influence, for this, internal processes are first restored.
Vitamin B9, or folic acid. The substance has a positive effect on the immune and circulatory system, thereby improving the nutrition of tissues and follicles. Vitamin affects the synthesis of cells, their growth.
Vitamin B10. This substance helps to increase the effectiveness of other B vitamins. It is distinguished by antioxidant properties that slow down the aging process. Vitamin helps to remove gray hair, smoothes wrinkles, cleanses the skin.
Vitamin B11, or L-carnitine. Involved in metabolic processes. Due to this, tissue repair and regeneration is accelerated.
Vitamin B12. It is called cyanocobalamin. The substance is involved in enzymatic reactions, avoids the development of anemia, thereby improving the nutrition of tissues, their respiratory function. Deficiency of cyanocobalamin (B12) can lead to nerve cell death.

Release forms

When choosing how to take a B vitamin, you must first determine the form and dosage. The drug is available in two forms: solution for injection and tablets or capsules for oral administration. Each of these forms has its own advantages and disadvantages.

The advantages of the solution for injections are high bioavailability and fast appearance of the result. Injection is not suitable for young children, because they do not always agree with injections, as well as for older people - it is more difficult for their body to cope with a possible overdose. This method of administration is more often used in acute hypovitaminosis and is carried out only as prescribed by a doctor.

Oral tablets or capsules are easy to use and help you control how much you take. But such agents have lower bioavailability due to the fact that some of the active substances are destroyed in the gastrointestinal tract. Oral forms can be drunk at home and are safer than injections.

Updated: 05/19/2019 13:53:59

Judge: Boris Kaganovich

*Overview of the best in the opinion of the editors of the site. About selection criteria. This material is subjective, is not an advertisement and does not serve as a guide to the purchase. Before buying, you need to consult with a specialist.

B vitamins are one of the most well-known means for maintaining the health of the nervous system. They are most often prescribed by neurologists for back pain, backache, diabetic and alcoholic polyneuropathy. But group B drugs can also be useful for practically healthy people who want to maintain their health.

What are B vitamins and why are they needed?

Vitamins are a group of highly active compounds that regulate all biochemical reactions in the body. All processes in cells occur under the influence of special proteins - enzymes. For them to start working, coenzymes are needed, that is, substances that, by joining the enzyme molecule itself, make it active. Vitamins play this role in the body. That is why, with their shortcomings, serious illnesses develop.

Group B includes 7 vitamins and 4 vitamin-like substances. Vitamins must be supplied from the outside, as they are not synthesized by the body. Vitamin-like substances are produced by the body, but in small quantities.

B vitamins:

IN 1- thiamine. Regulates the transmission of impulses in the nervous system, the tone of the heart muscle and smooth muscles of the gastrointestinal tract, participates in the transfer of genetic material during cell division and almost all metabolic processes in the body.
AT 2- riboflavin. Participates in the absorption of iron, the formation of red blood cells, the work of nerve cells, the synthesis of adrenal hormones.
AT 3- niacin. Also known as vitamin PP or nicotinic acid. Reduces blood pressure, improves microcirculation, participates in the work of the central nervous system, regulates the formation of red blood cells.
AT 5- pantothenic acid. It is part of coenzyme A (CoA) - the most important substance for the body, which is involved in all reactions that produce energy. Stimulates the synthesis of glucocorticoids by the adrenal glands, which is why it can be considered as an anti-inflammatory. Participates in immune responses and the production of neurotransmitters.
AT 6- pyridoxine. Regulates protein digestion, immunity, nervous system functions. Participates in the synthesis of hemoglobin and red blood cells.
AT 9- folic acid. Regulates hematopoiesis and development of the nervous system. It is especially important during the planning of pregnancy, since with its deficiency, defects in the brain and spinal cord occur in the fetus. On the other hand, with its excess, the activity of immune killer cells decreases.
AT 12- cobalamin (external factor of Castle). Necessary for normal hematopoiesis and the activity of the nervous system.

Vitamin-like substances:

AT 4- choline. It is part of the myelin sheath of nerve fibers. Source for the synthesis of the main CNS mediator - acetylcholine. Participates in the regulation of insulin activity, has hepatoprotective and lipotropic (protects the liver from fatty degeneration) properties.
AT 7- biotin. Also known as vitamin H or coenzyme R. Regulates protein and fat balance. A source of sulfur for the synthesis of proteins necessary for skin, hair, nails, and bone tissue.
AT 8- inositol. Promotes weight loss, participates in the regulation of cholesterol metabolism. slows down the development of atherosclerosis.
AT 10- para-aminobenzoic acid (bacterial vitamin H1). A powerful antioxidant, is involved in the thyroid gland and hematopoiesis.

As you can see, most of the B vitamins are somehow involved in maintaining the normal functioning of the nervous system, hematopoiesis, and immune responses. That is why the main area of their application is neurology.

Treatment of various kinds of neuritis, neuralgia, asthenic syndrome (general weakness) are the main indications for prescribing group B drugs. They are also recommended for sleep disorders (both insomnia and daytime sleepiness), an unstable psycho-emotional state (however, irritability and tearfulness can be manifestations asthenic syndrome). For preventive purposes, they are taken to maintain high level activity, both physical and mental, under stress, and to compensate for an unbalanced diet.

Many or few?

Anyone who has ever bought vitamins on foreign websites has paid attention to incredibly high dosages - sometimes they are a hundred times higher than the recommended daily dose indicated in the same instructions. At the same time, everyone heard about the danger of hypervitaminosis. It can, of course, be assumed that the manufacturers decided to massively poison their customers. But conspiracy theories aside, the situation is extremely interesting.

Those consumption rates that are usually indicated in the tables are called the rates of the recommended dietary supplement (RDA or Recommended Dietary Allowance). They were developed in the middle of the last century and since then they have been wandering from manual to manual with almost no changes. These norms stipulate the amount of vitamin in food, which helps to prevent diseases caused by its deficiency.

We draw the attention of readers - the RDA norms, which are cited in all medical guidelines, including domestic ones, are designed not to maintain an optimal level of health, but to prevent diseases. Those same diseases, like scurvy or beriberi, that modern man learns about from biology textbooks for high school, and not from reality.

But if we do not consider the absence of a disease to be the norm (and, according to WHO experts, health is a state of complete physical, mental and social well-being), then the indicated amounts of vitamins are clearly not enough to maintain an optimal state of health. Yes, and surveys, when a random sample of people studied the content of vitamins in the body, suggest that at least 60% of the population have their deficiency, and about a third - complex hypovitaminosis. It turns out that the norm for preventing a disease caused by vitamin deficiency and the norm that is optimal for health are different.

In addition, over the past half century, the nutrition of people has changed. Processed, refined products, semi-finished products, fast food began to dominate in the diet of most citizens. It is pointless to talk about the content of vitamins in such food - it means that they have to be replenished from other sources in much larger quantities than with a balanced diet.

That is why the concept of ONA (optimal nutrient allowance) appeared - the optimal intake of nutrients. These are the recommended daily dosages of vitamins, selected to achieve optimal health. They also take into account modern nutritional stereotypes. It is on them that most manufacturers of dietary supplements are guided. But the suggested dosages are many times higher than the usual recommendations.

Table of the need for vitamins of group B

Vitamin	Standard Norms


B3 (aka RR)

Based on what norms to select a group B complex, each reader is free to decide independently. An overdose of water-soluble vitamins, to which this group belongs, is unlikely when taking tablets - the body itself is able to regulate their absorption in the intestines and thus will not take “extra”.

But those who decide to choose drugs with higher doses will have to turn to the services of foreign online stores. In Russia, it is not allowed to register dietary supplements with the content of active substances exceeding the upper permissible consumption level specified in special regulatory documents. And this level is many times lower than recommended as optimal dosages, not to mention the maximum doses allowed by WHO. For example, for vitamin B1, the upper allowable consumption level according to Russian standards is 5 mg, and according to WHO, there is no upper limit, since it is extremely quickly excreted by the kidneys, which is why it does not have a toxic effect.

This restriction does not apply to medicines, since therapeutic dosages of vitamins can be higher than prophylactic ones, but in fact there are not so many drugs that are close in content to ONA standards in the free market.

By the way, paradoxically, vitamin complexes with an active substance content oriented to ONA standards can be found in offline sports nutrition stores.

Rating of the best B vitamins

The Best B Vitamins Available at Regular Pharmacies

In this section of the rating, we have selected funds that can be bought in ordinary offline pharmacies. Their advantages are availability, relatively low price and over-the-counter dispensing. Of the shortcomings, it should be noted that we found only one complex containing the entire group of B vitamins.

Multi-B complex Vitamir for the nervous system, hair and nails

This dietary supplement is positioned as a complex containing 11 B vitamins. In fact, it contains 7 B vitamins and 4 vitamin-like substances: choline (B4), biotin (B7), inositol (B8), para-aminobenzoic acid (B8). However, if we talk about group B as a complex, then the manufacturer almost did not depart from the truth.

The package contains 30 tablets, which is enough for a month at the recommended intake of 1 tablet per day. And given that the medicine is domestically produced, the cost of taking it turns out to be very humane.

Since the drug is registered as a dietary supplement, the only indication for its use is as an additional source of vitamins in food. Among the contraindications are pregnancy, lactation, individual intolerance.

Advantages

contains the entire complex of group B,
inexpensive.

Flaws

Pentovit

Contains B1, B3, B6, B9, B12. Available in packs of 50 tablets. It is recommended for asthenic conditions (overwork, weakness during recovery after a serious illness, etc.), neuralgia.

Of the shortcomings, a relatively long (for vitamins) list of contraindications should be noted. The manufacturer does not recommend the drug to pregnant women. Indeed, excessively high doses of nicotinamide have an embryotoxic effect. In a tablet of pentovit, it is 20 mg, that is, the amount does not exceed daily allowance according to the most conservative recommendations - if you limit yourself to one tablet. But the regimen recommended by the instructions is 2-3 tablets 3 times a day, which can really be too much during pregnancy.

Pentovit is not indicated for children under 18 years of age, people with chronic pancreatitis and gallstones.

Advantages

almost complete complex of group B,
low price.

Flaws

many contraindications.

Kombilipen

This medicine contains only three vitamins - B1, B6 and B12. But this is a complete analogue of Milgamma, a well-known and very beloved remedy by neurologists. The fact is that such a combination of vitamins in itself has analgesic properties, which allows you to reduce the dosage of anti-inflammatory drugs and reduce their harmful effects on the body. In addition, they contribute to the restoration of nervous tissue and protective myelin fibers.

The peculiarity of combilipen is a special, fat-soluble form of B1 - benfotiamine. This improves its bioavailability by several times. The dosages of all vitamins are quite high - 100 mg each of benfotiamine and pyridoxine, however, only 2 mg of cyanocobalamin. You need to take the medicine 1-3 tablets a day, depending on how you feel.

Contraindicated in children and in severe cardiovascular insufficiency.

Advantages

low price in comparison with analogues,
high doses of vitamins.

Flaws

prescription.

Salus vitamin B-complex

Contains B1, B2, B3, B5, B6, B12, biotin. That is, almost all B vitamins, with the exception of folic acid, and one vitamin-like substance.

The package contains 60 capsules, which is enough for 2 months of use. means of production German company, which positions itself as a manufacturer of naturopathic medicines - derived from natural ingredients, herbs, vegetables and fruits. Perhaps this explains the rather high cost of packaging for such a complex.

Advantages

a wide range of B vitamins,
natural origin.

Flaws

price.

The Best B Vitamins Available Online

These funds will have to be ordered online. They are suitable for those who prefer to take courses of high doses of vitamins, based on the theory of optimal micronutrient requirements. They can also be recommended to athletes, since regular physical activity inevitably entails an increased need for vitamins (as, indeed, for other nutrients). Many of the group B drugs mentioned in this section of the ranking are suitable for vegans. This is important because vitamin B12 can only be obtained from animal products and people on a vegan diet need to purposefully replenish its deficiency.

Contains a full B complex and vitamin-like substances of this group. It is named so because most of the vitamins (except B9) have a dosage of either 50 mg (B1, B2, B3, B5, B6) or 50 mcg (B12).

Take 1 capsule daily, with meals.

Available in capsules, suitable for vegans.

Advantages

a sufficiently high, but not excessive, amount of vitamins;
contains the full complex of B.
suitable for vegans.

Flaws

You need to order online and wait for delivery.

Doctor's Best, Fully Active B Complex with Quatrefolic

Contains B1, B2, B3, B5, B6, B9, B12 and biotin.

The peculiarity of this tool is a non-standard form of vitamin B9: Quatrefolic. It is a 5-methyltetrahydrofolic acid salt of glucosamine, characterized by increased bioavailability. It is necessary for people who have mutations that interfere with the normal metabolism of folic acid (testing for mutations in the folate cycle genes can be taken in most commercial laboratories). Most often, such mutations are found when examining women with recurrent miscarriage: a deficiency of folic acid in the body, caused by its reduced absorption, leads to the development of defects in the neural tube, heart, and genitourinary tract; missed pregnancy or premature detachment of the placenta. In addition, such mutations increase the likelihood of cardiovascular disease and certain types of cancer.

It is useless for people with such a pathology to take conventional folic acid preparations - they need funds with increased bioavailability.

The drug is available in cellulose-based capsules suitable for vegetarians.

Take 1 capsule per day.

Advantages

a special, easily digestible form of folic acid,
suitable for vegans.

Flaws

order online only.

Solgar B-Complex with Vitamin C Stress Formula, 250 Tablets

In addition to the full complex of B vitamins, it contains ascorbic acid and a mixture of natural plant extracts with antioxidant and cardioprotective properties. Contribute to the normalization of the nervous and immune systems.

Advantages

added a mixture of plant extracts to potentiate the main action.

Flaws

2 tablets per day.

Attention! This rating is subjective, is not an advertisement and does not serve as a guide to purchase. Before buying, you need to consult with a specialist.

B vitamins are essential for the human body. They support the functioning of the nervous system and the brain, improve mental abilities, participate in hematopoiesis, and regulate metabolism. Deficiency of these substances in the body causes the development of various serious illnesses. Fortunately, hypovitaminosis today is easy to defeat with the help of pharmaceuticals. People of all ages are advised to periodically take B vitamins in tablets.

What are the benefits of B vitamins to the body?

Group B includes the following useful compounds:

B 1 or thiamine;
B 2 or riboflavin;
B 3 or nicotinic acid;
B 4 or choline;
B 5 or pantothenic acid;
B 6 or pyridoxine;
B 7 or biotin;
B 8 or inositol;
B 9 or folic acid;
B 10 or para-aminobenzoic acid;
B 12 or cyanocobalamin.

Of the above vitamins, the most necessary for the body are B 1, B 2, B 6 and B 12. It is they who should be taken periodically in tablets. The remaining substances are needed by a person in a small amount, so they enter the body in abundance with food. The main symptom of vitamin B deficiency is chronic fatigue syndrome. In this regard, multivitamins based on group B are recommended for use in the following cases:

with high intellectual and mental stress;
with constant stress;
with diseases of the nervous system;
with violations of the functioning of the heart and circulatory system;
with any chronic pathologies;
with skin diseases;
with disorders of the digestive tract.

The main function of B vitamins is to provide the body with energy. It is these substances that play leading role in the formation of glucose from carbohydrates, the metabolism of proteins and lipids. Group B is rather unstable, compounds are not able to accumulate in tissues, quickly leave the body, and it is not always possible to eat fully and varied in the current realities. Therefore, both adults and children are periodically recommended to drink vitamin complexes.

Doctors usually prescribe B vitamins to patients either in injections or tablets. Tablets are more convenient to use than injections. In addition, many people do not like to take vitamin injections because of the rather strong pain.

List of the best vitamin preparations with B vitamins in the composition

Pharmacies today sell a huge number of good and effective vitamin complexes for adults and children. Below are the names and characteristics best vitamins group B tablets.

. A complex preparation based on vitamins of group B. Also in the composition of the tablets are retinol, tocopherol, ascorbic acid, mineral elements, ginseng extract. The drug is recommended for the prevention and treatment nervous disorders, improving physical and intellectual performance, eliminating the effects of stress. One tablet is taken at breakfast with water. Reception is carried out from 30 to 40 days. Contraindications: hypertension, epilepsy, hypercalcemia, increased nervous excitability, iron deficiency anemia. Do not take the drug to children under 16 years of age. Price: from 489 to 700 rubles.
. The preparation contains vitamins B 6 , B 9 and B 12 . The complex is intended for the prevention and treatment of atherosclerosis, ischemia, angiopathy, deterioration of blood circulation in the brain. One tablet should be taken per day. Reception lasts from 20 to 30 days. If the dosage is exceeded, side effects may occur: an allergic reaction, dizziness, headaches, sleep disturbance, nausea, excessive gas formation. Price: around 218 rubles.
Neurobex. Dragees containing vitamins B 1 , B 6 , B 12 . Indications for use: disorders of the nervous system and digestive tract, impaired blood circulation, dermatitis and acne caused by a deficiency of B vitamins. Adults take 1-2 tablets three times a day, children - one tablet once or twice a day. You can not use the drug for children under 2 years old, as well as for people suffering from erythrocytosis, polycythemia, thromboembolism. The medication may give side effects: nausea and allergic reaction, accompanied by redness and irritation of the skin. The cost of the drug varies from 300 to 350 rubles.
Neurovitan. A complex of vitamins, including thiamine, riboflavin, pyridoxine and cyanocobalamin. It is prescribed for pathologies of the nervous system, liver, heart, blood vessels. You can also use the drug to treat anemia, dermatitis, baldness, alcoholism, addiction to cigarettes. Daily dose for adults - 1 - 4 tablets, for children - up to 3 tablets, based on age. The course of admission is from 2 to 4 weeks. It is forbidden to combine the drug with alcoholic beverages. Price: 400-900 r.
Blagomax Complex of vitamins of group B. Dietary supplement, contains riboflavin, pyridoxine, cyanocobalamin, inositol, nicotinic, folic and pantothenic acids. Indications for use: constant stress, intellectual and physical overload. One capsule should be taken daily with food. Reception is carried out for a long time, at least 6 weeks. The drug is contraindicated in people prone to allergies, pregnant and breastfeeding women. Price: about 160 rubles.
B-complex 50. A vitamin complex that includes all the vitamins of group B, as well as medicinal plant components: parsley, rice bran, watercress, alfalfa. It is recommended when disorders of the nervous system and digestive organs occur, vision weakens, the condition of hair, skin, and nail plates worsens. One tablet should be taken daily after meals. The drug is contraindicated in pregnancy, lactation, allergies. Cost: about 1500 rubles.
Doppelherz active Magnesium + vitamins of group B. The composition of the drug includes thiamine, pyridoxine, cyanocobalamin, folic acid, magnesium. The complex is recommended for violations of the functioning of the heart, physical and mental overwork. One tablet should be taken per day. The appointment lasts a month. The drug is contraindicated in children, people prone to allergies, pregnant and breastfeeding women. Price: 244-282 rubles.

What vitamin complexes for children contain B vitamins?

For a child, B vitamins can be purchased not only in tablets, but also in syrup. The best children's vitamin preparations: Pikovit, Multi-tabs Kid, Adivit.

B vitamins must be taken properly so that they are absorbed well in the digestive tract. The drugs should be taken at the same time of day. You need to drink the tablets with water, you can not use too hot or cold drink. Vitamins can cause an allergic reaction, so the instructions should carefully look at how many tablets make up the daily dose, how long the intake should last.

Vitamin B was discovered back in 1912, and was discovered by a Polish scientist, Kazimir Funk. After some time, Funk's colleagues learned that this is not just one compound of substances, but a whole series, and all are united by a common feature: nitrogen is present in their molecules.

In other words, there is no single vitamin B, but a whole complex of substances, numbered from B1 to B20, has been isolated.

B vitamins: where are they found and what do they affect?

Despite their diversity, all B vitamins have a common feature: they help improve metabolism in the human body and normalize the immune and nervous systems.

All these vitamins are water-soluble and are quickly excreted from the body without accumulating in it. This means that it is necessary to replenish their reserves by taking special vitamin complexes and not forgetting food rich in these substances.

An important fact: doctors say that taking vitamins B in the complex has a much more noticeable effect than taking any one "variety" of the B vitamin.

Therefore, let's figure out what we should eat in order to reinforce the body with useful substances, which vitamins of group B secrete and why each of them is remarkable.

B1 (thiamine) - energy vitamin

Benefits: Helps convert fats, proteins, and carbohydrates into energy. Strengthens the nervous system and improves mental abilities.

Where it is contained: buckwheat and oatmeal, cereal shells, wholemeal bread, green peas, asparagus, pine nuts.

B2 (riboflavin) - beauty vitamin

Benefits: takes part in all metabolic processes of the body. It improves the condition of the skin, mucous membranes, nails and hair (hence the name "beauty vitamin"), is good for vision, promotes the production of hemoglobin.

Where it is contained: meat, offal (liver, kidneys), chicken eggs, mushrooms, cabbage (white cabbage, broccoli, etc.), pasta, white bread, peeled rice, buckwheat, cottage cheese.

B3 (nicotinic acid, vitamin PP) - vitamin of synthesis and metabolism

Benefits: helps to synthesize fats and proteins, promotes the production of energy from food, reduces the level of "bad cholesterol" in the blood. In addition, vitamin B3 helps to normalize venous and arterial pressure and stimulates the cardiovascular system.

Where it is found: fish, milk, egg yolk, nuts, liver, kidneys, yeast, buckwheat, green vegetables, legumes, meat, potatoes.

B4 (choline) - a vitamin responsible for blood sugar

Benefits: this vitamin is important for the normal functioning of the nervous system, it is useful for stress. In addition to its calming effect, B4 will help your thinking abilities. But most importantly, this vitamin regulates blood sugar levels. And it also normalizes fat metabolism, which has a positive effect on your weight.

Where it is contained: by-products (kidneys, liver), egg yolk, dairy products (cheese, cottage cheese), cabbage, spinach, legumes, various unrefined vegetable oils, meat, fish.

B5 (pantothenic acid) - healing vitamin

Benefits: helps wounds heal faster, promotes the synthesis of antibodies, fatty acids, hemoglobin, participates in the production of cellular energy.

Where it is contained: poultry, fish roe, heart, liver, kidneys, yolk, buckwheat and oatmeal, green leafy vegetables, peas, hazelnuts, yeast.

B6 (pyridoxine) - vitamin for the nervous system

Benefits: participates in the regulation of the activity of the nervous system, the production of red blood cells, the synthesis of hemoglobin and antibodies, contributes to the normal metabolism of carbohydrates.

Where it is contained: dairy products, fish, offal (kidneys, heart, liver), legumes, cereals, carrots, cabbage, spinach, potatoes, nuts (walnuts, hazelnuts), tomatoes, oranges, strawberries, yeast, wheat bran.

B7 (biotin, vitamin H, coenzyme R) - a vitamin for beautiful skin

Benefits: restores health and beauty to the skin and hair, is useful for bone and nervous tissue, regulates the activity of the sweat glands.

Where it is contained: yolk, liver, kidneys, yeast, tomatoes, soybeans, peanuts and other legumes, spinach, mushrooms, vegetables (cabbage, carrots, potatoes), dairy and meat products, fish.

B8 (inositol) - slimming vitamin

Benefits: helps to reduce weight, participates in the regulation of cholesterol levels, protects against atherosclerosis, is good for the brain.

Where it is found: yeast, bran and wheat germ, offal (brain, heart), bread, green peas, oranges, raisins, citrus fruits, carrots.

B9 (folic acid, vitamin M) - female vitamin

Benefits: indispensable for pregnant women, as it helps the fetus to develop properly. It is also necessary to take folic acid to children during the growth period of the body. Vitamin B9 contributes to the easy course of pregnancy, as well as the normalization of the emotional background before and after childbirth.

Where it is found: legumes, citrus fruits, yeast, liver, green leafy vegetables, nuts, yolk, fish, wholemeal flour, fruits (bananas, apricots, melons, oranges).

B12 (cobalamin) - vitamin against anemia

Benefits: participates in the processes of growth and activity of the nervous system, promotes the formation of red blood cells. Prevents the development of anemia.

Where it is contained: products of animal origin: meat, fish, poultry, offal, eggs, seafood.

B13 (orotic acid) - prenatal vitamin

Benefits: promotes the development of the fetus, has a beneficial effect on reproductive health, normalizes liver function.

Where it is contained: root vegetables, whey, cottage cheese, yeast, liver.

B17 (laetral) - vitamin against pain

Benefits: helps to cope with pain, slows down the aging process, improves metabolic processes. Useful in the fight against cancer.

Where it is contained: bones of fruits and berries (apples, plums, apricots, peaches, cherries).

What causes a lack of B vitamins?

So, we found out that B vitamins contribute to the normal functioning of all body systems, and therefore their deficiency can lead to a number of health problems. Adverse symptoms include:

disorders in the work of the nervous system;
poor condition of the skin, hair, nails;
muscle weakness;
pain in the joints;
numbness of the limbs;
labored breathing;
fatigue during physical exertion, rapid heartbeat;
insomnia;
loss of appetite;
dizziness.

As a rule, these symptoms appear in a complex, and only a competent specialist is able to determine the correct cause of the ailment.

Often, a lack of B vitamins leads to bad habits(smoking, frequent intake of alcohol and caffeine) and improper daily routine (lack of sleep, overwork). The doctor takes these factors into account when making a diagnosis.

Synthetic versus "natural": choosing vitamins

And yet - how best to make up for the lack of B vitamins in the body? Is it enough to eat right for this or should we not forget about synthetic vitamin-mineral complexes?

Let's try to imagine what the daily menu should look like in order to satisfy the body's need for B vitamins:

We should take 1.3-1.8 mg of vitamin B1 per day. This is 300 g of beans or 5 tablespoons of germinated wheat.
Add to this 1.8 mg of vitamin B2. Half a kilo of mushrooms or 1 egg.
Next, add 15 mg of vitamin B3. This is just 50 g of yeast or 90 g of liver.
Let's not forget about vitamin B5. The daily norm is 5-10 mg, and this is 200 g of chicken meat or 300 g of cheese.
Now let's take care of vitamin B6. On the day we need 2 mg of this substance, and this amount is contained in 50 g of yeast or 200 g of corn.

The arithmetic is hard. Vitamin complexes will come to the rescue, which already contain carefully calculated daily doses of B vitamins. This is an almost ideal way to replenish the lack of vitamins in the body. They are fully digestible and bring maximum benefit.

But, of course, any doctor will confirm that the most correct option is to eat foods rich in B vitamins and supplement your diet with vitamin-mineral complexes.

Today, a great variety of synthetic vitamins are presented on the shelves of pharmacies, and it is not always possible to understand which one should be chosen. SMC Best Clinic specialists will help you determine which vitamins will be most beneficial for you.

Make an appointment with our doctors and be always healthy!

Vitamins and useful elements are vital for a person. Their balance keeps the body healthy and beautiful. Hypovitaminosis of vitamins of group B is often observed. Therefore, it is required to take complexes in tablets and other forms.

Vitamin B is not one vitamin, but a whole composition of substances that are combined into one group. They are numbered from B1 to B12, some of them have their own name.

The main vitamins of group B:

Vitamin	Function
IN 1	It is called thiamine. It converts BJU into energy.
AT 2	It is called riboflavin. Vitamin is involved in metabolism and plays an important role for the skin, for the functioning of the visual organs.
AT 3	Its name is nicotinic acid or vitamin PP. It combines proteins and fats. Vitamin extracts energy from all substances that contain calories.
AT 5	Its name is pantothenic acid. It has a wound healing effect.
AT 6	Includes pyridoxine and pyridoxamine. Vitamin ensures the normal functioning of the nervous system, ensures the synthesis of hemoglobin, is involved in the work of carbohydrate metabolism.
AT 7	In another way, H or biotin. It helps release energy from substances that contain calories.
AT 9	Vitamin M, folic acid. Acid is essential for growth and development. It promotes cell division. Taking B9 is mandatory during the period of bearing a child, as it helps the fetus to develop.
AT 12	It is called cyanocobalamin. It affects the functioning of the nervous system.

B4, B8 and B10 are not vitamins, but are also important for the life of the human body. Vitamin-like substance B4 helps memory work and regulates the amount of insulin in the body. B8 is an antioxidant and antidepressant. It helps keep the skin healthy, and it also removes fat from the liver. B10 - activates the intestinal flora, helps the body absorb protein.

The benefits of B vitamins

B vitamins (in tablets, syrups and other types) carry positive effect on the body.

What does it consist of:

Indications for taking vitamins

You can not take vitamin complexes constantly, there are indications for taking them. Without them, excess vitamins in the body can lead to health problems.

Vitamins of group B in tablets have indications for taking:

Contraindications

In some cases, it is forbidden to take vitamin complexes.

Contraindications for admission:

Tendency to allergic reaction. Many of the B vitamins have allergic side effects.
AT 12 it is forbidden to use during pregnancy and lactation, with erythrocytosis and thromboembolism.
AT 6 should not be taken in conditions of severe stress and depression (loss of a loved one, deep depression, recent surgery, state of shock). It is forbidden to take B6 for diseases of the liver and thyroid gland, as well as intestinal pathologies, diagnosed anemia.
AT 5 it is forbidden to take in the presence of ulcers and during the period of use of the drug levodopa. Vitamin B2 should not be taken during the use of hormonal contraceptives and during the treatment of psychiatric diseases.
AT 3 not allowed to use with stomach ulcers, liver pathologies.
IN 1 not prescribed for allergy sufferers. Pharmacies sell vitamin complexes in which various vitamins of this group can be combined. Therefore, before buying and taking it, it is best to consult with your doctor (for example, a therapist, or a narrow specialist), or at least read the instructions for using the drug.

The best vitamin complexes. Instructions for use

Vitamins of group B in tablets are produced by various manufacturers.

List of the best of them:

Blagomax.
"Nutrilight".
"Beauty Complex".
BioMax.
Solgar.
"Lutein" for the eyes.
Vitrum.
"Complex Mega B".
"Pentovit".
Amway.
Gerimaks.
"Complivit".

Blagomax

Producer - Russia, NABISS company. Price - about 200 rubles. The vitamin complex is available in the form of capsules packed in a jar of 90 pcs.

What vitamins are included in the complex:

AT 2- good for the thyroid gland.
AT 3- helps to get rid of bad cholesterol.
AT 5- stimulates the production of glucocosteroids - hormones produced by the adrenal cortex.
AT 6- helps the growth of blood cells and the formation of antibodies.
AT 8- will protect the walls of blood vessels from fragility, help to normalize the functioning of the nervous system.
Folic acid- affects the growth and development of all tissues. It is indispensable when carrying a child.
AT 12- will not allow cells to experience oxygen starvation, maintains hemoglobin levels.

How to take Blacomax:

You need to take a vitamin complex in a course that lasts from 1 to 1.5 months.
Daily dose - 1 capsule.
You need to take the capsule with food.

Pros:

Acceptable price.
The drug is limited to 1 time per day.
Big package.

Cons - the capsule is difficult to swallow.

Nutrilight

Manufacturer - USA, Amway company. Price - 1100 - 1200 rubles. Nutrilight is available in the form of tablets, which are packaged in 100 pcs. in plastic jars. The complex contains 8 vitamins from group B.

Among them:

How to take a vitamin complex:

You need to take vitamins daily.
You need to take the tablets with meals.

Pros:

A large number of pcs. packaged.
1 dose for the whole day.

Minuses:

There are contraindications.
High price.

The Nutrilight brand of vitamins is based on 100% herbal ingredients. All of them are grown in the company's own production.

"Beauty complex"

Producer - Russia, VitaLine company. Price - 300-400 rubles. The complex is produced for women.

The drug is produced in the form of oblong tablets packed in blisters. A total of 30 pcs in a pack. In addition to B vitamins, dietary supplements contain other useful elements.

What is included in the "Beauty-Complex":

Zinc.
Iron.
Rutin.
Calcium.
Magnesium.
Beta carotene.
Vitamin E.
Vitamin D3.
Vitamin C.
Proanthocyanidins.

Pros:

The complex was created specifically taking into account the needs of the female body.
Packing is enough for 1 course.
Acceptable price.

Minuses:

There are contraindications.
An allergic reaction is possible.
The large size of the tablets makes it difficult to swallow.

"BioMax"

Producer - Russia, the company Valenta Pharmaceuticals. The price for a pack of 60 tablets is 300-350 rubles.

B vitamins in BioMax tablets are not the only useful elements in the composition of the product. The multivitamin complex includes 12 vitamins and 8 macronutrients to restore the balance of nutrients in the body. BAA is produced in packs of 30 and 60 pcs. Type - coated tablets with a specific odor.

Vitamins and macronutrients in the composition of the product:

Lipoic acid.
Vitamin C.
Vitamin A.
Vitamin B1.
Vitamin B2.
Folic acid.
Vitamin E.
Vitamin B12.
Vitamin B6.
Vitamin B5.
Vitamin RR.
Vitamin R.
Iron.
Zinc.
Calcium.
Copper.
Phosphorus.
Kolbat.
Magnesium.
Manganese.

How to take BioMax:

For children over 12 years of age and adults, the daily dosage is 1 tablet.
It must be taken after eating.
It is necessary to take dietary supplements in a course of 3 months.
It is necessary to take the tablet with a large amount of liquid - preferably clean water.
On the advice of a doctor, with severe beriberi and depletion of the body, it is allowed to increase the dosage to 2 tablets per day.

Pros:

Daily dose - 1 tablet.
Acceptable price.

Minuses:

Long course of admission -3 months.
There are contraindications.

Solgar

Manufacturer - USA, Solgar company. Price - about 1,200 rubles.

The drug is available in the form of round yellow tablets with a smell. They are packaged in a glass jar that holds 250 pcs. Solgar vitamin B complex, anti-stress formula - a complex of plant origin. Recommended by the manufacturer as a dietary supplement that supports immunity, provides energy to the body and the absence of stress.

What Solgar contains:

Vitamin C.
Vitamin B2.
Vitamin B3.
Vitamin B6.
Vitamin B9.
Vitamin B12.
Vitamin B7.
Vitamin B5.
Vitamin B4.
Vitamin B8.
A mixture of powdered kelp.
Leaves and stems of alfalfa.
Rose hip.

How to take Solgar:

You need to take dietary supplements courses. The duration of 1 course is 1-1.5 months.
You need to take Solgar daily.
Vitamins are taken with meals.
The number of doses per day - 2 times 1 tablet.

Pros:

plant composition.
Big package.

Minuses:

Not found in regular pharmacies.
High price.

"Lutein Intensive" for the eyes

Producer - Russia, the company Evalar. Price - 300 rubles.

This is a specially selected composition to improve the functioning of the visual organ. It allows you to accumulate lutein to the norm required by human vision. It is prescribed by ophthalmologists in case of deterioration of vision or for prevention in case of an observed tendency to worsen (frequent exposure to a computer screen, genetic predisposition).

What is collected in the dietary supplement:

lutein.
Zeaxanthin.
Vitamin A.
Vitamin B1.
Vitamin B6.
Vitamin B2.
Vitamin C.
A nicotinic acid.
Zinc.

How to take Lutein Intensive:

It is allowed to take Lutein for children over 14 years old and adults.
The daily dose of the drug is 2 tablets.
The number of receptions per day - 1.
You need to take Lutein in a course.

Pros:

Allowed to take teenagers from 14 years.
Acceptable price.

Minuses:

Take more than 1 time per day.
Small package.
There are contraindications.

"Vitrum"

Manufacturer - USA, Unipharm company. Price - 500 rubles. Universal dietary supplement containing 13 vitamins and 15 mineral components. "Vitrum" is produced in the form of dragees, packaged in jars of 60 pcs.

What vitamins are included in dietary supplements:

Vitamin E.
Vitamin A.
Vitamin D3.
Vitamin K1.
Vitamin B1.
Vitamin B5.
Vitamin B6.
Folic acid.
Vitamin B12.
Vitamin RR.
Vitamin H.
Vitamin B2.
Vitamin C.

How to take the universal complex "Vitrum":

Pros:

The price is acceptable.
One dose for the whole day.

Minuses:

There are contraindications.
An allergic reaction to the components of the dietary supplement is possible.

"Complex Mega-B"

Manufacturer - USA, Irwin Naturals Price - 1,800 rubles. These vitamins differ in the form of release. Standard vitamin complexes are sold in the form of tablets, and the Mega B Complex is sold in the form of gel capsules, they are filled with liquid. The dietary supplement includes medium chain triglycerides. They are rapidly absorbed into the bloodstream and become a source of energy.

Also, Irwin Naturals has patented the BioPerine complex, which is also found in dietary supplements. It increases the bioavailability of the drug and its absorption.

The entire list of vitamins and nutrients of the Mega B Complex:

Vitamin B5.
Vitamin B7.
Vitamin B3.
Thiamine.
Vitamin B2.
Niacin.
Vitamin B6.
Vitamin B12.
Medium chain triglycerides.
Dimethiglycine.
BioPerine Complex (it includes black pepper and ginger).

How to take Mega Complex B:

Addiction to food intake - consume dietary supplements while eating.
The number of receptions per day - 1.
The number of capsules consumed per day - 1 pc.

Pros:

The herbal composition of the product.
1 dose for the whole day.
A large number of useful substances collected in the composition.

Minuses:

High price.
There are contraindications.
An allergy may occur.
Difficult to find in pharmacies.

"Pentovit"

Manufacturer - Russia. Price - 150 rubles. The complex is recommended as an assistant to improve skin health.

What Pentovit includes:

Vitamin B1.
Vitamin B12.
Vitamin B6.
Folic acid.

How to take Pentovit:

Must be taken after eating.
The number of receptions per day - 3.
The number of tablets used for 1 dose is from 2 to 4. The dosage depends on the doctor's prescription.
You need to take the drug in a course that is up to 4 weeks.

Pentovit - popular B vitamins in tablets.

Pros:

Low price.
Helps maintain healthy skin, hair and nails.

Minuses:

Multiplicity of reception - 3 times.
A side effect, expressed in the form of an allergy, is possible.

Amway

Manufacturer - USA, Amway company. Price - 1,000 rubles. BAA has established itself as a source of additional energy during active physical activity, after suffering stress, or hypovitaminosis.

What is included in the dietary supplement:

How to take vitamins:

Every day you need to drink 1 tablet.
The tablet must be taken with meals.
Take the course, which is better to check with the observing doctor.

Pros:

1 dose for the whole day.
A large number of B vitamins in the composition.

Minuses:

High price.
There are contraindications.

Gerimaks

Manufacturer - Denmark. Price - 700-800 rubles. A vitamin complex that is recommended by manufacturers as an assistant during the rehabilitation period, after severe stress, or during high fatigue.

What is included in the dietary supplement:

Ginseng extract (root).
Thiamine.
Vitamin B2.
Vitamin B12.
Vitamin B9.
Vitamin C.
Vitamin E.
Vitamin A.
Magnesium.
Zinc.
Copper.
Molybdenum.
Chromium.
Manganese.
Nicotinamide.
Iron.
calcium pantothenate.

How to take Gerimaks:

The required amount of the drug per day with prophylactic administration is 1 tablet.
The manufacturer recommends taking Gerimaks in the morning.
Addiction to food intake - take after or during a meal.

Pros:

A large number of vitamins and useful elements in the composition.
Daily dose - 1 tablet.

Minuses:

High price.
You can not take the drug for epilepsy, irritability, with impaired absorption of iron.

"Complivit"

Producer - Russia, the company PharmStandard UfaVita. Price - for 60 tablets is approximately 300 rubles. Complivit involves the collection of beneficial substances that interact with each other. Vitamins are available in the form of tablets, convex on 2 sides, with a smell. Contains 8 minerals and 11 vitamins. Among them are vitamins of group B. The complex is packaged in jars of 30 or 60 tablets.

What is included:

Thiamine.
Riboflavin.
Pyridoxine.
Folic acid.
Cyanocobalamin.
Nicotinamide.
Ascorbic acid.
Rutoside.
Calcium.
Lipoic acid.
Iron.
Copper.
Calcium.
Zinc.
Cobalt.
Manganese.
Magnesium.
Phosphorus.
tocopherol acetate.

How to take Complivit:

You need to take a vitamin complex after a meal.
The number of doses per day is 1. Twice a day, it is allowed to take as directed by a doctor during acute beriberi.
The number of tablets consumed per day - 1 pc.

Pros:

A large number of vitamins in the composition of the complex.
Acceptable price.

Minuses:

There is a risk of an allergy to the components of the drug.
There are contraindications.

B vitamins are vital for the human body to maintain the health and normal functioning of all systems. With their shortage, complexes are prescribed, which are available in tablets or other forms.

Article formatting: Lozinsky Oleg

Video about B vitamins in tablets

Vitamins of group B, complex preparations: